General Information:

Id: 2,851 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
biofilm of P. aeruginosa strain PA14
article
Reference: Zhang L et al.(2011) Pseudomonas aeruginosa tssC1 links type VI secretion and biofilm-specific antibiotic resistance. J. Bacteriol. 193: 5510-5513 [PMID: 21784934]

Interaction Information:

Comment TssC1 is expressed in biofilms and important for biofilm-specific antibiotic resistance. The tssC1 gene was 18-fold more highly expressed in biofilm cells than in planktonic cells.
Formal Description
Interaction-ID: 26274

increases_quantity of

gene/protein

tssC1

Comment Hcp1 levels were significantly higher in biofilm cells than in planktonic cells, although expression was again slightly reduced in the tssC1 mutant. This result, combined with the tssC1 expression data, suggests that genes encoding components of the T6S system are induced during biofilm growth.
Formal Description
Interaction-ID: 26276

increases_quantity of

gene/protein

hcp1

Comment Hcp1 levels were significantly higher in biofilm cells than in planktonic cells, although expression was again slightly reduced in the tssC1 mutant. This result, combined with the tssC1 expression data, suggests that genes encoding components of the T6S system are induced during biofilm growth.
Formal Description
Interaction-ID: 28174

increases_activity of

process

T6SS-HSI-1