BTO:0002734 16-HBE14o cell, infected with P. aeruginosa strain PA3
Cuzick A et al.(2006) The type III pseudomonal exotoxin U activates the c-Jun NH2-terminal kinase pathway and increases human epithelial interleukin-8 production. Infect. Immun. 74: 4104-4113
It was shown that ExoU produces activation of the c-Jun NH2-terminal kinase (JNK) mitogen-activated protein kinase (MAPK) pathway and that this is required for efficient IL-8 production following infection.
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