General Information:

Id: 2,805 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
mice macrophages, infected with P. aeruginosa strain PA103 (expressing ExoU and ExoT)
article
Reference: Sutterwala FS et al.(2007) Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J. Exp. Med. 204: 3235-3245 [PMID: 18070936]

Interaction Information:

Comment ExoU induces macrophage cell death independently of IPAF.
Formal Description
Interaction-ID: 25873

gene/protein

exoU

increases_activity of

process

cell death

in macrophages; infected with P. aeruginosa strain PA103 (expressing ExoU)