General Information:

Id: 2,781 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
article/cited
Reference: Schweizer HP and Choi KH(2011) Pseudomonas aeruginosa aerobic fatty acid desaturase DesB is important for virulence factor production. Arch. Microbiol. 193: 227-234 [PMID: 21184216]

Interaction Information:

Comment Elastin degradation by the concerted activity of both P. aeruginosa LasB and LasA elastases is regarded as a major virulence determinant during acute infection, thus causing pulmonary hemorrhages during invasive P. aeruginosa infections. (cited information)
Formal Description
Interaction-ID: 25714

gene/protein

lasB

decreases_quantity of

gene/protein

ELN

Drugbank entries Show/Hide entries for lasB or ELN
Comment Elastin degradation by the concerted activity of both P. aeruginosa LasB and LasA elastases is regarded as a major virulence determinant during acute infection, thus causing pulmonary hemorrhages during invasive P. aeruginosa infections. (cited information)
Formal Description
Interaction-ID: 33889

process

P. aeruginosa infection, acute

increases_activity of

gene/protein

lasB

Drugbank entries Show/Hide entries for lasB
Comment Elastin degradation by the concerted activity of both P. aeruginosa LasB and LasA elastases is regarded as a major virulence determinant during acute infection, thus causing pulmonary hemorrhages during invasive P. aeruginosa infections. (cited information)
Formal Description
Interaction-ID: 40199

gene/protein

lasB

increases_activity of

phenotype

lung hemorrhage

Drugbank entries Show/Hide entries for lasB