General Information:

Id: 2,745 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
BTO:0000018 A-549 cell, infected with P. aeruginosa strain PAO1
article
Reference: Hurley BP et al.(2011) Selective eicosanoid-generating capacity of cytoplasmic phospholipase A2 in Pseudomonas aeruginosa-infected epithelial cells. Am. J. Physiol. Lung Cell Mol. Physiol. 300: L286-L294 [PMID: 21097525]

Interaction Information:

Comment Treatment of A549 cells with either PMA or PAO1 results in a noticeable increase in expression of the phosphorylated form of cPLA2-alpha, while the overall cPLA2-alpha expression levels remain unchanged.
Formal Description
Interaction-ID: 25414

process

P. aeruginosa infection

increases_activity of

gene/protein

PLA2G4A

by phosphorylation
Drugbank entries Show/Hide entries for PLA2G4A