General Information:

Id: 2,742 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
BTO:0000018 A-549 cell, infected with P. aeruginosa strain PAK or PAO1
Reference: Shin HS and Ha UH(2011) Up-regulation of human bradykinin B1 receptor by secreted components of Pseudomonas aeruginosa via a NF-kappaB pathway in epithelial cells. FEMS Immunol. Med. Microbiol. 63: 418-426 [PMID: 22092568]

Interaction Information:

Comment Pseudomonas aeruginosa up-regulates the expression of hB1R mRNA. The ability to induce hB1R is well conserved among P. aeruginosa strains, and the optimal induction was observed 4 h post treatment at an MOI (multiplicity of infection) of 10.
Formal Description
Interaction-ID: 25395


P. aeruginosa infection

increases_expression of



in airway epithelial A549 cells; optimum reached at 4 h post treatment at an MOI of 10