General Information:

Id: 2,655 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
article
Reference: Anderson DM et al.(2011) Ubiquitin and ubiquitin-modified proteins activate the Pseudomonas aeruginosa T3SS cytotoxin, ExoU Mol. Microbiol. 82: 1454-1467 [PMID: 22040088]

Interaction Information:

Comment Polyubiquitin molecules associate with and activate ExoU with the greatest efficiency in vitro suggesting that either the size of the cofactor or multiple interaction sites within ExoU are important for phospholipase activity.
Formal Description
Interaction-ID: 25066

gene/protein

exoU

decreases_quantity of

drug/chemical compound

Phospholipid