General Information:

Id: 2,595 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
P. aeruginosa strain PAK and PA14
article
Reference: Moscoso JA et al.(2011) The Pseudomonas aeruginosa sensor RetS switches type III and type VI secretion via c-di-GMP signalling Environ. Microbiol. 13: 3128-3138 [PMID: 21955777]

Interaction Information:

Comment An artificial increase in c-di-GMP levels, upon overproduction of an active diguanylate cyclase (WspR or PA1120), controls the T3SS and the T6SS in an inverse manner. This T3SS/T6SS switch is similar to what was previously observed in a strain with a retS mutation.
Formal Description
Interaction-ID: 24555

gene/protein

wspR

decreases_activity of

process

T3SS

if wspR is overexpressed