General Information:

Id: 2,592 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
Reference: Moscoso JA et al.(2011) The Pseudomonas aeruginosa sensor RetS switches type III and type VI secretion via c-di-GMP signalling Environ. Microbiol. 13: 3128-3138 [PMID: 21955777]

Interaction Information:

Comment The second messenger c-di-GMP is utilized as a signal for transition between the planktonic and sessile lifestyles. High c-di-GMP levels promote biofilm formation and chronic infections, while low c-di-GMP levels favour swimming and virulence.
Formal Description
Interaction-ID: 24481

drug/chemical compound


increases_activity of

if c-di-GMP level is high