General Information:

Id: 2,586 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Diaz MR et al.(2011) Intrinsic and Extrinsic Regulation of Type III Secretion Gene Expression in Pseudomonas Aeruginosa. Front Microbiol 2: 89 [PMID: 21833328]

Interaction Information:

Comment Besides ExsA only one additional transcriptional factor (PsrA) is known to directly regulate the T3SS.
Formal Description
Interaction-ID: 24379

gene/protein

psrA

increases_expression of

complex/PPI

T3SS complex

Comment The DNA-binding activity of PsrA is directly inhibited by long chain fatty acids. Indeed T3SS gene expression is reduced in the presence of long chain fatty acids, although the biological significance of this observation is unclear.
Formal Description
Interaction-ID: 24380

drug/chemical compound

Long-chain fatty acid

decreases_activity of

gene/protein

psrA