General Information:

Id: 2,565 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Bernard CS et al.(2010) Nooks and crannies in type VI secretion regulation. J. Bacteriol. 192: 3850-3860 [PMID: 20511495]

Interaction Information:

Comment In P. aeruginosa, a pair of sensor kinases, RetS and LadS, regulates the expression of the HSI-1 T6SS gene cluster. T3SS and T6SS are inversely regulated. RetS is an activator of the expression of T3SS genes but represses genes involved in biofilm formation and T6SS expression. LadS has reciprocal effects.
Formal Description
Interaction-ID: 24057

gene/protein

ladS

increases_activity of