General Information:

Id: 2,541 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
P. aeruginosa strain PAO1
article
Reference: Upritchard HG et al.(2008) Immunoproteomics to examine cystic fibrosis host interactions with extracellular Pseudomonas aeruginosa proteins. Infect. Immun. 76: 4624-4632 [PMID: 18663005]

Interaction Information:

Comment The analysis of sera from four patients with CF detected multiple extracellular proteins. The identities of the selected proteins were determined by antisera. Production of at least four of these proteins (azurin and three proteases: elastase, PrpL, and PasP) is governed by quorum sensing, consistent with active bacterial quorum sensing in the lungs of CF patients.
Formal Description
Interaction-ID: 23649

process

P. aeruginosa infection, chronic

increases_quantity of

gene/protein

lasB

in sera of CF patients (from stationary-phase cultures)
Drugbank entries Show/Hide entries for lasB