General Information:

Id: 2,524 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
BTO:0000018 A-549 cell; BTO:0004603 HBE cell, infected with P. aeruginisa CF clinical isolates
article
Reference: Bauman SJ and Kuehn MJ(2009) Pseudomonas aeruginosa vesicles associate with and are internalized by human lung epithelial cells. BMC Microbiol. 9: 26 [PMID: 19192306]

Interaction Information:

Comment CF isolates of P. aeruginosa abundantly secrete PaAP (PA2939), an aminopeptidase that associates with the surface of vesicles. The conditions present in infected CF lungs promote upregulation of P. aeruginosa PaAP and production of vesicles that contain PaAP.
Formal Description
Interaction-ID: 23509

process

P. aeruginosa infection, chronic

increases_quantity of

gene/protein

paaP

in CF isolates