General Information:

Id: 2,518 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Dean P(2011) Functional domains and motifs of bacterial type III effector proteins and their roles in infection. FEMS Microbiol. Rev. 35: 1100-1125 [PMID: 21517912]

Interaction Information:

Comment ExoY is an effector produced by some strains of P. aeruginosa that shares homology to the calmodulin-activated adenylate cyclase toxins CyaA (Bordetella) and EF (Bacillus). The absence of the calmodulin-binding site suggests that unlike other bacterial adenylate cyclases, ExoY is not activated by calmodulin and this was indeed the case, although ExoY still requires a host cytosolic factor for activation.
Formal Description
Interaction-ID: 23444

gene/protein

CALM1

NOT affects_activity of

gene/protein

exoY

Drugbank entries Show/Hide entries for CALM1