General Information:

Id: 2,504 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
3T3 fibroblasts from mice or HeLa cells, infected with P. aeruginosa strain K (PAK)
article
Reference: Pielage JF et al.(2008) RNAi screen reveals an Abl kinase-dependent host cell pathway involved in Pseudomonas aeruginosa internalization. PLoS Pathog. 4 [PMID: 18369477]

Interaction Information:

Comment Abl tyrosine kinase is required for invasion of P. aeruginosa in mammalian cells.
Formal Description
Interaction-ID: 23316

process

P. aeruginosa infection

increases_activity of

gene/protein

ABL1

Drugbank entries Show/Hide entries for ABL1