General Information:

Id: 2,464 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Bleves S et al.(2010) Protein secretion systems in Pseudomonas aeruginosa: A wealth of pathogenic weapons. Int. J. Med. Microbiol. 300: 534-543 [PMID: 20947426]

Interaction Information:

Comment Except for the T4SS (type IV secretion system), all the other secretion machines described in Gram-negative bacteria have been identified in P. aeruginosa. Thanks to this secretion arsenal, P. aeruginosa is able to produce and release a very broad variety of exoproteins.
Formal Description
Interaction-ID: 22795

process

P. aeruginosa infection

increases_activity of

process

T3SS

Comment The following secreted proteins are associated with T3SS (protein secretion by the type III secretion system). Strains of P. aeruginosa have different combinations of genes encoding T3SS effectors and can be divided into 2 groups. The cytotoxic strains possess exoU, exoT, and sometimes exoY (e.g. strain PA103 or PA14), whereas invasive isolates possess exoS, exoT, and often exoY (e.g. strain PAO1 or PAK).
Formal Description
Interaction-ID: 23018

process

T3SS

increases_transport of

gene/protein

exoU

into the host cell
Comment The following secreted proteins are associated with T3SS (protein secretion by the type III secretion system). Strains of P. aeruginosa have different combinations of genes encoding T3SS effectors and can be divided into 2 groups. The cytotoxic strains possess exoU, exoT, and sometimes exoY (e.g. strain PA103 or PA14), whereas invasive isolates possess exoS, exoT, and often exoY (e.g. strain PAO1 or PAK).
Formal Description
Interaction-ID: 23033

process

T3SS

increases_transport of

gene/protein

exoT

into the host cell
Comment The following secreted proteins are associated with T3SS (protein secretion by the type III secretion system). Strains of P. aeruginosa have different combinations of genes encoding T3SS effectors and can be divided into 2 groups. The cytotoxic strains possess exoU, exoT, and sometimes exoY (e.g. strain PA103 or PA14), whereas invasive isolates possess exoS, exoT, and often exoY (e.g. strain PAO1 or PAK).
Formal Description
Interaction-ID: 23034

process

T3SS

increases_transport of

gene/protein

exoY

into the host cell
Comment The following secreted proteins are associated with T3SS (protein secretion by the type III secretion system). Strains of P. aeruginosa have different combinations of genes encoding T3SS effectors and can be divided into 2 groups. The cytotoxic strains possess exoU, exoT, and sometimes exoY (e.g. strain PA103 or PA14), whereas invasive isolates possess exoS, exoT, and often exoY (e.g. strain PAO1 or PAK).
Formal Description
Interaction-ID: 23035

process

T3SS

increases_transport of

gene/protein

exoS

into the host cell