General Information:

Id: 2,400 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
BTO:0000567 HeLa cell, infected with P. aeruginosa strain PAK
Reference: Jia J et al.(2003) c-Jun NH2-terminal kinase-mediated signaling is essential for Pseudomonas aeruginosa ExoS-induced apoptosis. Infect. Immun. 71: 3361-3370 [PMID: 12761120]

Interaction Information:

Comment ExoS activates proapoptotic pathways through activation of JNK1/2 leading ultimately to cytochrome c release and activation of caspases.
Formal Description
Interaction-ID: 21380



increases_activity of