General Information:

Id: 2,398 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
BTO:0000182 HT-29 cell, infected with P. aeruginosa strain 388
article
Reference: Fraylick JE et al.(2002) Eukaryotic cell determination of ExoS ADP-ribosyltransferase substrate specificity. Biochem. Biophys. Res. Commun. 291: 91-100 [PMID: 11829467]

Interaction Information:

Comment Analyses of the Rho family of LMMG-proteins (low-molecular-mass G-proteins) for possible ADP-ribosylation identified a single shift in the mass of Rac1 following bacterial translocation of ExoS, but no alteration in the mobility of Cdc42 or RhoA, B, C was detected.
Formal Description
Interaction-ID: 21356

gene/protein

exoS

affects_activity of

gene/protein

RAC1

by ADP-ribosylation in vitro and in vivo
Drugbank entries Show/Hide entries for RAC1