General Information:

Id: 2,398 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
BTO:0000182 HT-29 cell, infected with P. aeruginosa strain 388
article
Reference: Fraylick JE et al.(2002) Eukaryotic cell determination of ExoS ADP-ribosyltransferase substrate specificity. Biochem. Biophys. Res. Commun. 291: 91-100 [PMID: 11829467]

Interaction Information:

Comment Two-dimensional electrophoresis comparisons of substrate modifications by ExoS in vitro to that following bacterial translocation into HT-29 epithelial cells identified Ras, Ral, and Rab proteins and Rac1 as in vivo substrates of ExoS ADPRT activity.
Formal Description
Interaction-ID: 21353

gene/protein

exoS

affects_activity of

gene/protein

RAB7

by ADP-ribosylation in vitro and in vivo