General Information:

Id: 2,346
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
BTO:0000018 A-549 cell, human alveolar adenocarcinoma cell line, infected with P. aeruginosa strain PAK
article
Reference: Ichikawa JK et al.(2005) Genome-wide analysis of host responses to the Pseudomonas aeruginosa type III secretion system yields synergistic effects. Cell. Microbiol. 7: 1635-1646 [PMID: 16207250]

Interaction Information:

Comment The following genes were upregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20457

gene/protein

exoS

increases_expression of

gene/protein

HIF1A

Drugbank entries Show/Hide entries for HIF1A
Comment The following genes were upregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20458

gene/protein

exoS

increases_expression of

gene/protein

DUSP10

Comment The following genes were upregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20459

gene/protein

exoS

increases_expression of

gene/protein

STAT5A

Comment The following genes were upregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20460

gene/protein

exoS

increases_expression of

gene/protein

MAP3K8

Comment The following genes were upregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20461

gene/protein

exoS

increases_expression of

gene/protein

PDE4D

Drugbank entries Show/Hide entries for PDE4D
Comment The following genes were upregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20463

gene/protein

exoS

increases_expression of

gene/protein

G3BP1

Comment The following genes were upregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20464

gene/protein

exoS

increases_expression of

gene/protein

GDI2

Comment The following genes were upregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20465

gene/protein

exoS

increases_expression of

gene/protein

IFNGR2

Drugbank entries Show/Hide entries for IFNGR2
Comment The following genes were upregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20476

gene/protein

exoS

increases_expression of

gene/protein

BCL2A1

Comment The following genes were upregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20477

gene/protein

exoS

increases_expression of

gene/protein

ZNF217

Comment The following genes were downregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20478

gene/protein

exoS

decreases_expression of

gene/protein

BAX

Comment The following genes were downregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20479

gene/protein

exoS

decreases_expression of

gene/protein

ADRM1

Comment The following genes were downregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20480

gene/protein

exoS

decreases_expression of

gene/protein

IL4

Comment The following genes were downregulated in response to P. aeruginosa effector ExoS.
Formal Description
Interaction-ID: 20486

gene/protein

exoS

decreases_expression of

gene/protein

PTMS

Comment The following genes were upregulated in response to P. aeruginosa effector ExoT.
Formal Description
Interaction-ID: 20491

gene/protein

exoT

increases_expression of

gene/protein

IL1B

Drugbank entries Show/Hide entries for IL1B
Comment The following genes were upregulated in response to P. aeruginosa effector ExoT.
Formal Description
Interaction-ID: 20495

gene/protein

exoT

increases_expression of

gene/protein

TNFAIP6

Comment The following genes were upregulated in response to P. aeruginosa effector ExoT.
Formal Description
Interaction-ID: 20498

gene/protein

exoT

increases_expression of

gene/protein

NAMPT

Drugbank entries Show/Hide entries for NAMPT
Comment The following genes were upregulated in response to P. aeruginosa effector ExoT.
Formal Description
Interaction-ID: 20499

gene/protein

exoT

increases_expression of

gene/protein

CSF3

Comment The following genes were downregulated in response to P. aeruginosa effector ExoT.
Formal Description
Interaction-ID: 20504

gene/protein

exoT

decreases_expression of

gene/protein

CDC42

Drugbank entries Show/Hide entries for CDC42
Comment The following genes were downregulated in response to P. aeruginosa effector ExoT.
Formal Description
Interaction-ID: 20506

gene/protein

exoT

decreases_expression of

gene/protein

CEACAM6

Comment The following gene was upregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20567

gene/protein

exoY

increases_expression of

gene/protein

IL11

Comment The following genes were downregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20568

gene/protein

exoY

decreases_expression of

gene/protein

FGG

Drugbank entries Show/Hide entries for FGG
Comment The following genes were downregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20569

gene/protein

exoY

decreases_expression of

gene/protein

FGB

Drugbank entries Show/Hide entries for FGB
Comment The following genes were downregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20570

gene/protein

exoY

decreases_expression of

gene/protein

ANXA13

Comment The following genes were downregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20571

gene/protein

exoY

decreases_expression of

gene/protein

VTN

Drugbank entries Show/Hide entries for VTN
Comment The following genes were downregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20572

gene/protein

exoY

decreases_expression of

gene/protein

S100P

Drugbank entries Show/Hide entries for S100P
Comment The following genes were downregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20573

gene/protein

exoY

decreases_expression of

gene/protein

ERBB3

Comment The following genes were downregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20574

gene/protein

exoY

decreases_expression of

gene/protein

ABCC5

Comment The following genes were downregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20575

gene/protein

exoY

decreases_expression of

gene/protein

CEACAM5

Drugbank entries Show/Hide entries for CEACAM5
Comment The following genes were downregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20576

gene/protein

exoY

decreases_expression of

gene/protein

MUC5AC

Comment The following genes were downregulated in response to P. aeruginosa effector ExoY.
Formal Description
Interaction-ID: 20577

gene/protein

exoY

decreases_expression of

gene/protein

GYPE