General Information:

Id: 2,336 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Hauser AR(2009) The type III secretion system of Pseudomonas aeruginosa: infection by injection. Nat. Rev. Microbiol. 7: 654-665 [PMID: 19680249]

Interaction Information:

Comment Similar to ExoS, ExoT residues 78-235 contain GAP activity towards Rac, Rho, and Cdc42. This activity appears to be very similar to that of the N-terminus of ExoS and causes reversible disruption of the actin cytoskeleton.
Formal Description
Interaction-ID: 20379

gene/protein

exoT

decreases_activity of

gene/protein

RAC1

Drugbank entries Show/Hide entries for RAC1