General Information:

Id: 2,336 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Hauser AR(2009) The type III secretion system of Pseudomonas aeruginosa: infection by injection. Nat. Rev. Microbiol. 7: 654-665 [PMID: 19680249]

Interaction Information:

Comment ExoS catalyzes the transfer of ADP-ribose to many different host proteins. Substrates of special interest are Ras and the ezrin, radixin and moesin (ERM) family of proteins. ADP-ribosylation of ERM proteins prevents their phosphorylation, resulting in inactivation.
Formal Description
Interaction-ID: 20375

gene/protein

exoS

decreases_activity of

gene/protein

RDX

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