General Information:

Id: 2,285 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Heeb S et al.(2011) Quinolones: from antibiotics to autoinducers. FEMS Microbiol. Rev. 35: 247-274 [PMID: 20738404]

Interaction Information:

Comment The expression of the phnAB genes is induced 14-22-fold, in line with the upregulation of the pqsABCDE operon (17-19-fold) in clinical isolates from sputum in CF (cystic fibrosis) patients compared with the expression of these genes in a morpholinepropanesulphonic acid-buffered glucose medium.
Formal Description
Interaction-ID: 19613

process

P. aeruginosa infection, chronic

increases_expression of

gene/protein

phnA

in sputum of CF patients
Drugbank entries Show/Hide entries for phnA