General Information:

Id: 2,285 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Heeb S et al.(2011) Quinolones: from antibiotics to autoinducers. FEMS Microbiol. Rev. 35: 247-274 [PMID: 20738404]

Interaction Information:

Comment Clinical isolates from sputum in CF (cystic fibrosis) patients showed that they all produced PQS and also HHQ, HQNO, NQNO and UQNO. In addition, there was a correlation between the levels of PQS and the bacterial sample load.
Formal Description
Interaction-ID: 19608

process

P. aeruginosa infection, chronic

increases_quantity of

drug/chemical compound

2-Heptyl-3-hydroxy-4-quinolone, PQS

in sputum of CF patients