General Information:

Id: 2,285 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Heeb S et al.(2011) Quinolones: from antibiotics to autoinducers. FEMS Microbiol. Rev. 35: 247-274 [PMID: 20738404]

Interaction Information:

Comment PQS positively controlled the expression of the lasB (elastase) gene. It was later shown that this effect was considerably enhanced when PQS and C4-HSL acted synergistically to upregulate lasB expression.
Formal Description
Interaction-ID: 19572

drug/chemical compound

2-Heptyl-3-hydroxy-4-quinolone, PQS

increases_expression of

gene/protein

lasB

Drugbank entries Show/Hide entries for lasB