General Information:

Id: 2,214 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Dubern JF and Diggle SP(2008) Quorum sensing by 2-alkyl-4-quinolones in Pseudomonas aeruginosa and other bacterial species. Mol Biosyst 4: 882-888 [PMID: 18704225]

Interaction Information:

Comment HHQ can also potentiate PqsR binding to the pqsABCDE promoter. Not only that, PQS is fully dispensable, as a pqsH mutant which produces HHQ but no PQS displayed normal PqsR-dependent gene expression and virulence.
Formal Description
Interaction-ID: 18680

drug/chemical compound

2-Heptyl-4-quinolone, HHQ

increases_activity of

gene/protein

mvfR