General Information:

Id: 2,144 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Williams BJ et al.(2010) Pseudomonas aeruginosa: host defence in lung diseases. Respirology 15: 1037-1056 [PMID: 20723140]

Interaction Information:

Comment The LasR quorum sensing pheromone, N-(3-oxododecanoyl)-L-homoserine lactone, can directly interact with host cells inducing apoptosis in neutrophils and stimulating IL-8 production in bronchial epithelial cells.
Formal Description
Interaction-ID: 17879

drug/chemical compound

N-(3-Oxododecanoyl)-HSL

increases_quantity of

gene/protein

CXCL8

in bronchial epithelial cells