General Information:

Id: 2,120 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Parsek MR and Greenberg EP(2000) Acyl-homoserine lactone quorum sensing in gram-negative bacteria: a signaling mechanism involved in associations with higher organisms. Proc. Natl. Acad. Sci. U.S.A. 97: 8789-8793 [PMID: 10922036]

Interaction Information:

Comment LasR is a transcriptional regulator that responds primarily to the LasI-generated signal, 3OC12-HSL, and RhlR is a transcriptional regulator that responds best to the RhlI-generated signal, C4-HSL.
Formal Description
Interaction-ID: 17349

drug/chemical compound

N-Butyryl-HSL

increases_activity of

gene/protein

rhlR

in P.aeruginosa