General Information:

Id: 2,120 (click here to show other Interactions for entry)
Diseases: Pseudomonas aeruginosa diseases
pathogen-host system
Pseudomonas aeruginosa/mammalia
review
Reference: Parsek MR and Greenberg EP(2000) Acyl-homoserine lactone quorum sensing in gram-negative bacteria: a signaling mechanism involved in associations with higher organisms. Proc. Natl. Acad. Sci. U.S.A. 97: 8789-8793 [PMID: 10922036]

Interaction Information:

Comment Acyl-homoserine lactone signaling in P. aeruginosa is a model for the relationships among quorum sensing, pathogenesis, and community behavior. In the P. aeruginosa model, quorum sensing is required for normal biofilm maturation and for virulence.
Formal Description
Interaction-ID: 17343

process

Acyl-HSL quorum sensing

increases_activity of

in P.aeruginosa
Comment Bacteria in these mature biofilms are phenotypically resistant to microbicidal agents, including antibiotics. Thus biofilms cause many different types of chronic or persistent bacterial infections.
Formal Description
Interaction-ID: 17378

increases_activity of

process

antibiotic resistance

in P.aeruginosa