General Information:

Id: 2,103 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
Reference: Ghigo E et al.(2009) Intracellular life of Coxiella burnetii in macrophages Ann. N. Y. Acad. Sci. 1166: 55-66 [PMID: 19538264]

Interaction Information:

Comment Adding IFN-gamma to C. burnetii-infected monocytes stimulates phagosome-lysosome fusion, but does not affect vacuolar pH. The treatment of monocytes by IFN-gamma prior C. burnetii infection induces the alkalinization of C. burnetii vacuoles independently of the V-H+-ATPase exclusion.
Formal Description
Interaction-ID: 37802



affects_activity of

in C. burnetii-infected monocytes; treated with IFN-gamma prior to infection
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