General Information:

Id: 2,103 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
review
Reference: Ghigo E et al.(2009) Intracellular life of Coxiella burnetii in macrophages Ann. N. Y. Acad. Sci. 1166: 55-66 [PMID: 19538264]

Interaction Information:

Comment C. burnetii-stimulated macrophages induces the expression of M2 polarization-related genes. The expression of M1 macrophage activation-associated genes such as those encoding TNF, CD80, CCR7, and TLR2 were inhibited.
Formal Description
Interaction-ID: 34979

process

atypical M2 polarization

NOT increases_quantity of

gene/protein

TNF

in macrophages
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