General Information:

Id: 2,062 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
Reference: Voth DE and Heinzen RA(2007) Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii Cell. Microbiol. 9: 829-840 [PMID: 17381428]

Interaction Information:

Comment Coxiella protein synthesis is required for early autophagosome interactions that promote stalling of PV maturation. Protein effectors of this process presumably target host factors that regulate vesicular trafficking and are likely delivered to the cytosol via the activity of a type IV secretion system (T4SS) that has homology to the Dot/Icm T4SS of Legionella.
Formal Description
Interaction-ID: 17050


Coxiella burnetii infection

increases_activity of