General Information:

Id: 2,062 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
Reference: Voth DE and Heinzen RA(2007) Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii Cell. Microbiol. 9: 829-840 [PMID: 17381428]

Interaction Information:

Comment Pathogen interactions with autophagosomes can have either beneficial or detrimental effects. Coxiella clearly benefits from autophagy as induction of this pathway increases the number of infected cells, the size of the PV, and the extent of Coxiella replication. These effects are abolished when infected cells are treated with the autophagy inhibitors wortmannin and 3-methyladenine.
Formal Description
Interaction-ID: 17043


Coxiella burnetii infection

increases_activity of