General Information:

Id: 2,061 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
review
Reference: Shannon JG and Heinzen RA(2009) Adaptive immunity to the obligate intracellular pathogen Coxiella burnetii Immunol. Res. 43: 138-148 [PMID: 18813881]

Interaction Information:

Comment Repeated passage of C. burnetii phase I organisms in vitro results in conversion to a phase II phenotype where bacteria produce a truncated LPS molecule lacking the terminal O-antigen sugars. Phase II C. burnetii are severely attenuated and cannot establish an infection in an immunocompetent host.
Formal Description
Interaction-ID: 16524

organism

Coxiella burnetii, phase II

NOT increases_activity of

process

Coxiella burnetii infection

in an immunocompetent host