General Information:

Id: 2,017 (click here to show other Interactions for entry)
Diseases: Q fever
pathogen-host system
Coxiella burnetii/mammalia
BTO:0000798 BeWo cell, infected with Coxiella burnetii
article
Reference: Ben Amara A et al.(2010) Coxiella burnetii, the agent of Q fever, replicates within trophoblasts and induces a unique transcriptional response PLoS ONE 5 [PMID: 21179488]

Interaction Information:

Comment In the network organized around IL6ST (IL6 signal transducer), 25 genes were down-regulated in response to Coxiella burnetii infection, some were specific for C. burnetii, including IGF2, GFAP and PCSK1, as shown in an microarray approach.
Formal Description
Interaction-ID: 16082

process

Coxiella burnetii infection

decreases_expression of

gene/protein

PCSK1

in BeWo trophoblasts
Drugbank entries Show/Hide entries for PCSK1