General Information:

Id: 3,873 (click here to show other Interactions for entry)
Mus musculus
B6.SJL-Ptprc a/BoAiTac
Reference: Nemeth MJ et al.(2007) Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation Proc. Natl. Acad. Sci. U.S.A. 104 [PMID: 17881570]

Interaction Information:

Comment Both (Wnt3a: 2.4-fold; Wnt5a: 3-fold) significantly increased the percentage of total cells actively undergoing apoptosis from 1% to 3%. [Method: Il-7Ralpha- KSL cells (isolated from TOPGAL mice) cultured with recombinant Wnt3a or Wnt5a, Annexin V and PI staining]
Formal Description
Interaction-ID: 39030

gene/protein

Wnt3a

increases_activity of

in CD127-KSL cells in vitro