General Information:

Id: 3,158 (click here to show other Interactions for entry)
Mus musculus
OP9-Wnt3a secreting stromal cell or OP-9-control cells
Reference: Malhotra S and Kincade PW(2009) Canonical Wnt pathway signaling suppresses VCAM-1 expression by marrow stromal and hematopoietic cells Exp. Hematol. 37: 19-30 [PMID: 18951693]

Interaction Information:

Comment Hematopoietic cells formed very few cobblestones when cultured on Wnt3a transduced rather than wild-type stromal cells that do not make Wnt3a. [Method: cobblestone formation assay, OP9 stromal cells Wnt3a secreting or control]
Formal Description
Interaction-ID: 29052

gene/protein

Wnt3a

decreases_activity of

process

cobblestone formation

of HSC (KSL) in vitro